CLEAR CELL CARCINOMA OVARY

CLEAR CELL CARCINOMA OVARY

 

Clear cell carcinoma ovary: Tumor cells which are cuboidal to polygonal arranged in tubulocystic pattern with eosinophilic material in the lumen of the tubules (H&E,X 100)

Clear cell carcinoma ovary: Tumor cells which are cuboidal to polygonal arranged in tubulocystic pattern with eosinophilic material in the lumen of the tubules (H&E,X 100)

 

Clear cell carcinoma ovary: polygonal tumor cells arranged in nests and lobules separated by fibrous septa. Few foci shows cysts lined by tumor cells having moderate to abundant eosinophilic granular cytoplasm (H&E,X200)

Clear cell carcinoma ovary: polygonal tumor cells arranged in nests and lobules separated by fibrous septa. Few foci shows cysts lined by tumor cells having moderate to abundant clear to eosinophilic granular cytoplasm (H&E,X200)

 

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules separated by fibrous septa. Tumor cells have clear to eosinophilic cytoplasm. Nuclei is vesicular with some of them showing nuclleoli (H&E,X200)

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules separated by fibrous septa. Tumor cells have clear to eosinophilic cytoplasm. Nuclei is vesicular with some of them showing nucleoli (H&E,X200)

 

Clear cell carcinoma ovary: polygonal tumor cells arranged in tubulocystic pattern and in sheets. Most of the tumor cells have eosinophilic cytoplasm and few foci shows cells with clear cytoplasm (H&E, X100)

Clear cell carcinoma ovary: polygonal tumor cells arranged in tubulocystic pattern and in sheets. Most of the tumor cells have eosinophilic cytoplasm and few foci shows cells with clear cytoplasm (H&E, X100)

 

Clear cell carcinoma ovary: large cystic areas with papillae lined by tumor cells and have fibrotic core. cystic spaces contain eosinophilic necrotic material. Few foci shows sheets of tumor cells (H&E,X50)

Clear cell carcinoma ovary: large cystic areas with papillae lined by tumor cells and have fibrotic core. cystic spaces contain eosinophilic necrotic material. Few foci shows sheets of tumor cells (H&E,X50)

 

Clear cell carcinoma ovary: large cystic spaces lined by tumor cells. One foci (right upper) shows solid sheets of tumor cells (H&E,X50)

Clear cell carcinoma ovary: large cystic spaces lined by tumor cells. One foci (right upper) shows solid sheets of tumor cells (H&E,X50)

 

Clear cell carcinoma ovary: large cystic spaces lined by tumor cells (upper left). Adjacent area shows polygonal tumor cells arranged in lobules and nests. Tumor cells have clear to eosinophilic cytoplasm (H&E,X50)

Clear cell carcinoma ovary: large cystic spaces lined by tumor cells (upper left). Adjacent area shows polygonal tumor cells arranged in lobules and nests. Tumor cells have clear to eosinophilic cytoplasm (H&E,X50)

 

Clear cell carcinoma ovary: polygonal tumor cells arranged in lobules, nests. Cystic spaces with eosinophilic material is seen . central area shows tumor cells arranged in papillae (H&E,X50)

Clear cell carcinoma ovary: polygonal tumor cells arranged in lobules, nests. Cystic spaces with eosinophilic material is seen . central area shows tumor cells arranged in papillae (H&E,X50)

 

Clear cell carcinoma ovary: polygonal tumor cells arranged in lobules, nests. Cystic spaces with eosinophilic material is seen . central area shows tumor cells arranged in papillae (H&E,X100)

Clear cell carcinoma ovary: polygonal tumor cells arranged in lobules, nests. Cystic spaces with eosinophilic material is seen . central area shows tumor cells arranged in papillae (H&E,X100)

 

Clear cell carcinoma ovary: Large cystic spaces lined sheets of tumor cells and with eosinophilic material in lumen. Tumor cells have clear cytoplasm and vesicular nuclei. Tubulocystic pattern is also noted (right) (H&E,X100)

Clear cell carcinoma ovary: Large cystic spaces lined sheets of tumor cells and with eosinophilic material in lumen. Tumor cells have clear cytoplasm and vesicular nuclei. Tubulocystic pattern is also noted (upper right) (H&E,X100)

 

Clear cell carcinoma ovary: polygonal tumor cells having clear to eosinophilic cytoplasm arranged in tubular and cystic pattern (H&E,X100)

Clear cell carcinoma ovary: polygonal tumor cells having clear to eosinophilic cytoplasm arranged in tubular and cystic pattern (H&E,X100)

 

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules and nests separated by thin fibrous septs. Tumor cells have clear cytoplasm and vesicular nuclei with nucleoli (H&E,X200)

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules and nests separated by thin fibrous septs. Tumor cells have clear cytoplasm and vesicular nuclei with nucleoli (H&E,X200)

 

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules and nests separated by thin fibrous septs. Tumor cells have clear cytoplasm and vesicular round, oval and triangular nuclei with nucleoli (H&E,X400)

Clear cell carcinoma ovary: solid variant with sheets of polygonal tumor cells arranged in lobules and nests separated by thin fibrous septs. Tumor cells have clear cytoplasm and vesicular round, oval and triangular nuclei with nucleoli (H&E,X400)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal to flattened tumor cells. Few foci shows hyaline globules in lumen (H&E,X100)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal to flattened tumor cells. Few foci shows hyaline globules in lumen (H&E,X100)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal to flattened tumor cells. Few foci shows hyaline globules in lumen (H&E,X200)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal to flattened tumor cells. Few foci shows hyaline globules in lumen (H&E,X200)

 

Clear cell carcinoma ovary: Tubulocystic pattern lined by cuboidal tumor cells. Few foci shows tumor cells having clear cytoplasm and vesicular nuclei with nucleoli (H&E,X200)

Clear cell carcinoma ovary: Tubulocystic pattern lined by cuboidal tumor cells. Few foci shows tumor cells having clear cytoplasm and vesicular nuclei with nucleoli.  Lumen of the tubules show hyaline globules (H&E,X200)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal cells. Lumen of the tubules shows eosinophilic material (H&E,X100)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by single layer of cuboidal cells. Lumen of the tubules shows eosinophilic material (H&E,X100)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by flattened tumor cells (H&E,X100)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by flattened tumor cells (H&E,X100)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by flattened tumor cells (H&E,X400)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by flattened tumor cells (H&E,X400)

 

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by tumor cells having hobnail appearance with nucleus protruding into lumen (H&E,X400)

Clear cell carcinoma ovary: Tubulocystic pattern with tubules lined by tumor cells having hobnail appearance with nucleus protruding into lumen (H&E,X400)

 

Clear cell carcinoma ovary: tumor cells arranged in tubulocystic pattern with areas of necrosis (lower right) (H&E,X50)

Clear cell carcinoma ovary: tumor cells arranged in tubulocystic pattern with areas of necrosis (lower right) (H&E,X100)