Causes of Cushings syndrome

Causes of Cushings syndrome

The causes are broadly divided into exogenous and endogenous causes

• Exogenous causes – exogenous administration of Glucocorticoids

• Endogenous causes – 

  • ACTH dependent 

    • Pituitary adenoma

    • Ectopic corticotropin syndrome

  • ACTH independent

    • Adrenal adenoma

    • Adrenal carcinoma

    • Macronodular hyperplasia

    • Primary pigmented nodular adrenal disease

    • McCune-Albright syndrome

 

Reference

Anirban Maitra. The Endocrine system.In: Robbins and Cotran Pathologic basis of disease.9th edition.volume II.chapter 24. pp 1073-1141.