Diagramatic representation of two patterns of fibroadenoma
Diagramatic representation of two patterns of fibroadenoma
Fibrosdenoma consists of proliferating epithelial and mesenchymal components
Stroma proliferates around tubular ducts (pericanalicular pattern) or compressed cleft like ducts (Intracanalicular pattern)
Ducts are lined by luminal epithelial cells and outer myoepithelial cells. Luminal epithelial cells may show hyperplasia. Other changes like atrophic change or apocrine change or squamous metaplasia can also occur
Stroma shows abundant hyalinization and myxoid change.