NEUTROPHILS WITH BILIRUBIN CRYSTALS

Neutrophils with bilirubin crystals 
  • Neutrophils in neonates and children with marked hyperbilirubinemia may show neutrophil crystals.
  • These crystals are more common in septicemia patients than patiens with hemolyic disease
  • Formation of crystals are considered to be invitro phenomenon as these are specifically seen in blood samples collected in EDTA 
Reference
Adnan Qureshi and Naveed Akhtar. Bilirubin inclusions in neonatal neutrophils. Blood 2017;130:1601. 
Bilirubin crystals in neutrophils

Bilirubin crystals in neutrophils. (Courtesy Dr.E.Tanusha. Senior resident, CMC, Chittoor)

Bilirubin crystals in neutrophils

Bilirubin crystals in neutrophils (Courtesy Dr.E.Tanusha. Senior resident, CMC, Chittoor)

Bilirubin crystals in neutrophils

Bilirubin crystals in neutrophils (Courtesy Dr.E.Tanusha. Senior resident, CMC, Chittoor)